DiskPulse is capable of monitoring multiple disks or directories. In order to monitor multiple directories, press the 'Manage Profile' button, which is located on the right side of the profile selector combo box and specify all the disks or directories that should be monitored.

All the specified disks and/or directories, including all subdirectories, will be monitored simultaneously and all file system changes will be reported in a single, interleaved view. Users requiring separate change lists for multiple disks or directories may start multiple instances of the DiskPulse GUI application and select a different monitoring profile in each of them.

Another option is to start the monitoring operation is using the standard the Windows Explorer application. Open Windows Explorer, select one or more disks or directories to monitor, press the right mouse button and select the 'DiskPulse – Monitor Changes' menu item.